Right now, the big question in aesthetic skin care is, what are polynucleotides (PNs)? Despite their presence for over 4 decades, they are now gaining immense recognition for their incredible ability to accelerate hair growth, diminish scars and stretch marks, and reduce or slow down the signs of ageing across various areas such as the face, eyes, neck, décolletage, and hands. 

Polynucleotide treatment is a concentrated serum containing purified DNA fragments sourced from the semen of freshwater fish, notably salmon and trout. The serum is meticulously produced in a European facility, ensuring it’s not only highly purified but also safe and effective. It penetrates the deeper layers of the skin or scalp through injections, facilitating its rejuvenating effects. Polynucleotides are the culmination of 70 years of dedicated research and over 100 published studies, all corroborating their safety and efficacy. 

At Cardiff Cosmetic Clinic, our focus is on harnessing the regenerative potential of polynucleotide treatments for the face, hair, and eyes. It can be used independently or in combination with other aesthetic procedures to optimise results, such as laser skin resurfacing treatments, radiofrequency treatments, dermal fillers, chemical skin peels, and microneedling treatments.

Treatment Summary

    • Procedure Time
      30 Minutes
    • Anaesthetic
      Not Required
    • Back to work
    • Full recovery
      Same day
    • Duration of results
      Long term

      Risks & complications

What are polynucleotides for the face?

Polynucleotides offer a powerful solution for facial rejuvenation, particularly in combating the early or advanced signs of ageing. During each treatment session, we gently inject the polynucleotide serum into targeted areas on the forehead, the delicate arches of the eyebrows, or the contours of the cheekbones. As the serum permeates the skin, its regenerative properties spring into action, nourishing, brightening, and hydrating the skin from within. By promoting cellular turnover, the treatment smoothes wrinkles, while also lifting and firming loose skin, including the troublesome jowl area.

Following polynucleotide injections, you will notice discernible improvements in skin quality and texture, accompanied by a reduction in skin roughness and a notable enhancement in elasticity and tone.

We highly recommend combining our polynucleotide face treatment with our range of cutting-edge procedures, including Dermalux Tri-Wave MD, Morpheus8, microneedling, chemical peels, and dermal fillers. Polynucleotides help prepare the skin for these treatments, ensuring you enjoy the maximum benefits in the least amount of time. 

What are polynucleotides for the eyes?

The skin around the eye area is exceptionally delicate, making it prone to accelerated ageing and the development of crow’s feet, drooping eyelids (ptosis), and sagging eyebrows (eyebrow ptosis).

Our polynucleotide injection for the eye area is specifically designed to address the periorbital region and the arches of the eyebrows. It can be used as a preventive measure or to combat the existing signs of ageing.

The benefits of our polynucleotide eye treatments are many. Not only do they refresh the skin around the eye, leaving you looking more revived and less tired, but they also improve the overall quality and glow of your skin. By enhancing skin structure, elasticity, and tightness, these treatments visibly reduce fine lines and sagging, even in severely affected areas.

As with Polynucleotides for the face, Polynucleotides under the eyes or around this area complement other procedures offered at Cardiff Cosmetic Clinic. This ensures you achieve the best results in revitalising your eye area and restoring a refreshed, radiant appearance.

What are polynucleotides for hair loss?

If you’re grappling with hair loss, hair thinning, a receding hairline, or balding, polynucleotides offer a revitalising solution that nourishes both the scalp tissue and hair follicles for accelerated and sustainable hair growth results.

During each session, we apply a topical anaesthetic cream to your scalp, ensuring your comfort throughout the procedure. Subsequently, the polynucleotide serum is delicately injected at a depth ranging between 2 and 4 millimetres.

The polynucleotide injection for hair stimulates growth, strengthens each strand, and promotes increased thickness for improved hair health. Additionally, it seamlessly integrates with other hair loss treatments to amplify results, whether as a post-surgery supplement following a hair transplant or in conjunction with PRP hair loss treatments. Read more about how we combine polynucleotides with PRP treatments


Frequently Asked Questions

  • How many treatments do I need?

    The number of polynucleotide treatments varies from person to person because it’s based on individual factors. In general, for the face or eyes, we recommend 4 treatment sessions spaced every 2 or 3 weeks. If you’re looking to address facial scarring using polynucleotides, a slightly different approach is recommended. A total of 2 sessions, spaced 3 weeks apart, is typically sufficient to achieve noticeable improvements in scar appearance and texture. Additionally, for maintenance, 1 treatment every 3 or 4 months helps sustain the rejuvenating and repairing effects.

    For hair loss, we recommend a tailored regimen of 4 to 6 treatment sessions, spaced 3 weeks apart, followed by a maintenance course comprising 1 injection every 3 months.

  • How quickly will I see results?

    The benefits of Polynucleotide treatments for the eyes and face unfold gradually, typically showing visible results within a few weeks. Over several months, the skin will show signs of significant improvement in texture, firmness, and hydration. Polynucleotide hair treatments generally reduce hair shedding within 3 months and improve thickness and texture within 6 months. The best results in hair density are usually seen between 6 and 12 months.

  • How long do results last?

    Following the initial series of polynucleotide treatments for the face, eyes, or hair, the results can last for several months. To sustain these benefits, follow-up or maintenance treatments are advised, typically at intervals of every 3 or 4 months.

  • What parts of the body can polynucleotide treatments be used on?

    Polynucleotides serve diverse medical and aesthetic purposes across different areas of the body. Specifically, when applied to the hair, they are exclusively used on the scalp, eyebrows, and beard to stimulate hair growth. For facial and eye treatments, polynucleotides target specific areas such as the forehead, arches of the eyebrows, cheek area, and periorbital region.

  • Is there any aftercare following a PN treatment?

    Yes, aftercare plays an essential role in optimising results and minimising potential side effects. Here are some general guidelines to follow: Avoid touching the treated area after the procedure to prevent irritation or infection and refrain from physical activity for 24 hours following treatments.

  • Is downtime required after treatments?

    Polynucleotide treatments offer the advantage of minimal downtime. Following the procedure, most individuals can quickly resume their normal activities without significant interruption.

  • Are there any risks?

    Polynucleotides boast an outstanding safety profile, characterised by minimal side effects such as mild discomfort, irritation, or pain at the treatment site. Importantly, there have been no reported cases of severe side effects, as the treatment is well-tolerated and highly biocompatible with living tissues, ensuring its safety and efficacy

Request a Consultation

Here at Cardiff Cosmetic Clinic, we are an aesthetic skin care clinic where our team has a care-focussed approach to your treatments! So, if you have any questions, or would like to discuss the best Cosmetic Treatment for you, request a free
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